Acyclovir Information

Why is Acyclovir prescribed?

Acyclovir is used to treat herpes zoster, (the painful rash known as shingles). It is also prescribed to relieve the sores caused by genital herpes.

Is there any contraindications to individuals using Acyclovir?

Acyclovir should not be used by anyone with a weak immune system, such as those with HIV infection or those who have undergone a bone marrow or kidney transplant. Acyclovir can cause serious side effects, including death, in such people. Also, avoid Acyclovir if you are sensitive to it or the similar drug acyclovir (Zovirax).

How should you use Acyclovir?

If you are taking Acyclovir for shingles, you should start using it as soon as possible after your physician has made a diagnosis. Clinical studies have shown that the medication is most effective against shingles if treatment is initiated within the first 72 hours of initial symptoms.

If you are using Acyclovir for genital herpes, begin taking the meication at the first sign of an attack. The medication may not be effective if you wait longer than 72 hours after the first attack or 24 hours after a later attack. You may take Acyclovir with or without food.

What if I miss a dose of Acyclovir?

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.
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What side effects may occur with Acyclovir?

Side effects cannot be anticipated. However, if any develop or change in intensity, inform your physician as soon as possible.
Clinical side effects may include: Abdominal pain, aggressive behavior, agitation, allergic reactions, confusion, depression, diarrhea, dizziness, facial swelling, hallucinations, headache, high blood pressure, joint pain, mania, menstrual problems, nausea, rapid heartbeat, rash, vomiting

Are there any special warnings concerning Acyclovir?

High doses of Acyclovir have proved dangerous in people whose immune system is compromised because of HIV infection, bone marrow transplant, or kidney transplant. If your kidneys are not functioning properly, or you are taking drugs that may damage the kidneys such as Neomycin or Streptomycin, Acyclovir can make your condition worse or affect your central nervous system (brain and spinal cord).
Acyclovir relieves the symptoms of genital herpes, but it is not a cure. Please note: There is also no evidence that Acyclovir will prevent transmission of genital herpes. To avoid spreading the infection, do not have sexual intercourse during a flare-up. Acyclovir is not intended for use in children.

Possible food and drug interactions when taking Acyclovir

If you are taking Acyclovir with certain other drugs, the effect of either drug could be increased, decreased, or altered. Check with your doctor before combining Acyclovir with cimetidine (Tagamet) and/or probenecid (Benemid).

Can Acyclovir be taking if you are pregnant or breast feeding?

The effects of Acyclovir during pregnancy and breastfeeding have not been adequately reviewed in clinical studies. If you are pregnant or plan to become pregnant, notify your physician prior to taking the medication. If you are nursing and need to use Acyclovir, your physician may advise you to discontinue breastfeeding while using the medication.

What are the Recommended dosages of Acyclovir?

Shingles - the usual dose is 1 gram 3 times a day for 7 days.

Genital Herpes - the usual dose for the first attack is 1 gram twice a day for 10 days. For later attacks, the dose is 500 milligrams twice a day for 5 days. To keep the condition from returning, the dose is 1 gram once a day.

If your kidneys are not functioning well, your physician may decide to reduce the dosage.

What if there is an overdose of Acyclovir?

When taken by people with kidney disorders excessive doses of Acyclovir have been known to cause psychological problems and kidney failure. If you suspect an overdose, call 911 or visit your local emergency room or clinic.

How is Acyclovir stored?

Store Acyclovir at room temperature between 59 and 77 degrees F (15 to 25 degrees C) away from heat and light. Keep this and all medications out of the reach of children.