| Valtrex (Valacyclovir hydrochloride)
Information
Why is Valtrex prescribed?
Valtrex is used to treat herpes zoster, (the painful
rash known as shingles). It is also prescribed to relieve
the sores caused by genital herpes.
Is there any contraindications to individuals
using Valtrex?
Valtrex should not be used by anyone with a weak immune
system, such as those with HIV infection or those who
have undergone a bone marrow or kidney transplant. Valtrex
can cause serious side effects, including death, in
such people. Also, avoid Valtrex if you are sensitive
to it or the similar drug acyclovir (Zovirax).
How should you use Valtrex?
If you are taking Valtrex for shingles, you should
start using it as soon as possible after your physician
has made a diagnosis. Clinical studies have shown that
the medication is most effective against shingles if
treatment is initiated within the first 72 hours of
initial symptoms.
If you are using Valtrex for genital herpes, begin
taking the meication at the first sign of an attack.
The medication may not be effective if you wait longer
than 72 hours after the first attack or 24 hours after
a later attack. You may take Valtrex with or without
food.
What if I miss a dose of Valtrex?
Take it as soon as you remember. If it is almost time
for your next dose, skip the one you missed and go back
to your regular schedule. Do not take 2 doses at the
same time.
.
What side effects may occur with Valtrex?
Side effects cannot be anticipated. However, if any
develop or change in intensity, inform your physician
as soon as possible.
Clinical side effects may include: Abdominal pain, aggressive
behavior, agitation, allergic reactions, confusion,
depression, diarrhea, dizziness, facial swelling, hallucinations,
headache, high blood pressure, joint pain, mania, menstrual
problems, nausea, rapid heartbeat, rash, vomiting
Are there any special warnings concerning Valtrex?
High doses of Valtrex have proved dangerous in people
whose immune system is compromised because of HIV infection,
bone marrow transplant, or kidney transplant. If your
kidneys are not functioning properly, or you are taking
drugs that may damage the kidneys such as Neomycin or
Streptomycin, Valtrex can make your condition worse
or affect your central nervous system (brain and spinal
cord).
Valtrex relieves the symptoms of genital herpes, but
it is not a cure. Please note: There is also no evidence
that Valtrex will prevent transmission of genital herpes.
To avoid spreading the infection, do not have sexual
intercourse during a flare-up. Valtrex is not intended
for use in children.
Possible food and drug interactions when taking
Valtrex
If you are taking Valtrex with certain other drugs,
the effect of either drug could be increased, decreased,
or altered. Check with your doctor before combining
Valtrex with cimetidine (Tagamet) and/or probenecid
(Benemid).
Can Valtrex be taking if you are pregnant or
breast feeding?
The effects of Valtrex during pregnancy and breastfeeding
have not been adequately reviewed in clinical studies.
If you are pregnant or plan to become pregnant, notify
your physician prior to taking the medication. If you
are nursing and need to use Valtrex, your physician
may advise you to discontinue breastfeeding while using
the medication.
What are the Recommended dosages of Valtrex?
Shingles - the usual dose is 1 gram 3 times a day for
7 days.
Genital Herpes - the usual dose for the first attack
is 1 gram twice a day for 10 days. For later attacks,
the dose is 500 milligrams twice a day for 5 days. To
keep the condition from returning, the dose is 1 gram
once a day.
If your kidneys are not functioning well, your physician
may decide to reduce the dosage.
What if there is an overdose of Valtrex?
When taken by people with kidney disorders excessive
doses of Valtrex have been known to cause psychological
problems and kidney failure. If you suspect an overdose,
call 911 or visit your local emergency room or clinic.
How is Valtrex stored?
Store Valtrex at room temperature between 59 and 77
degrees F (15 to 25 degrees C) away from heat and light.
Keep this and all medications out of the reach of children.
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